Edit |   |
Antigenic Specificity | FUS (C-term), 499-526 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FUS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-526 amino acids from the C-terminal region of human FUS. This gene encodes a multifunctional protein component ofthe heterogeneous nuclear ribonucleoprotein (hnRNP) complex. ThehnRNP complex is involved in pre-mRNA splicing and the export offully processed mRNA to the cytoplasm. This protein belongs to theFET family of RNA-binding proteins which have been implicated incellular processes that include regulation of gene expression,maintenance of genomic integrity and mRNA/microRNA processing.Alternative splicing results in multiple transcript variants.Defects in this gene result in amyotrophic lateral scler |
Immunogen | n/a |
Other Names | [RNA-binding protein FUS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMp75; Translocated in liposarcoma protein; FUS; TLS] |
Gene, Accession # | [FUS], Gene ID: 2521, NCBI: NP_001164105.1, UniProt: P35637 |
Catalog # | MBS9201324 |
Price | $165, $370 |
Order / More Info | FUS (C-term), 499-526 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kim, S.H., et al. J. Biol. Chem. 285(44):34097-34105(2010) Mackenzie, I.R., et al. Lancet Neurol 9(10):995-1007(2010) Yan, J., et al. Neurology 75(9):807-814(2010) Waibel, S., et al. Neurology 75(9):815-817(2010) Baumer, D., et al. Neurology 75(7):611-618(2010) |