FUS (C-term), 499-526 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFUS (C-term), 499-526
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted reactivity: bovine)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionThis FUS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-526 amino acids from the C-terminal region of human FUS. This gene encodes a multifunctional protein component ofthe heterogeneous nuclear ribonucleoprotein (hnRNP) complex. ThehnRNP complex is involved in pre-mRNA splicing and the export offully processed mRNA to the cytoplasm. This protein belongs to theFET family of RNA-binding proteins which have been implicated incellular processes that include regulation of gene expression,maintenance of genomic integrity and mRNA/microRNA processing.Alternative splicing results in multiple transcript variants.Defects in this gene result in amyotrophic lateral scler
Immunogenn/a
Other Names[RNA-binding protein FUS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMp75; Translocated in liposarcoma protein; FUS; TLS]
Gene, Accession #[FUS], Gene ID: 2521, NCBI: NP_001164105.1, UniProt: P35637
Catalog #MBS9201324
Price$165, $370
Order / More InfoFUS (C-term), 499-526 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKim, S.H., et al. J. Biol. Chem. 285(44):34097-34105(2010) Mackenzie, I.R., et al. Lancet Neurol 9(10):995-1007(2010) Yan, J., et al. Neurology 75(9):807-814(2010) Waibel, S., et al. Neurology 75(9):815-817(2010) Baumer, D., et al. Neurology 75(7):611-618(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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