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Antigenic Specificity | VPS52 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061). |
Immunogen | Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA) |
Other Names | [Vacuolar protein sorting-associated protein 52 homolog; SAC2 suppressor of actin mutations 2-like protein; VPS52; SACM2L] |
Gene, Accession # | [VPS52], Gene ID: 6293, NCBI: NP_001276104.1, UniProt: Q8N1B4 |
Catalog # | MBS7108523 |
Price | $160, $235 |
Order / More Info | VPS52 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |