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Antigenic Specificity | MAGED1 (Center) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed. |
Immunogen | Immunogen: This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the central region of human MAGED1. |
Other Names | [NRAGE; DLXIN-1] |
Gene, Accession # | [MAGED1], Gene ID: 9500, NCBI: Q9Y5V3.3, UniProt: Q9Y5V3 |
Catalog # | MBS8558835 |
Price | $280 |
Order / More Info | MAGED1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |