Cleaved LC3B, 89-122 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cleaved LC3B, 89-122 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.25 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Cleaved LC3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-122 amino acids from human Cleaved LC3B. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microt |
| Immunogen | n/a |
| Other Names | [Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta; MAP1LC3B; MAP1ALC3] |
| Gene, Accession # | [MAP1LC3B], Gene ID: 81631, NCBI: NP_073729.1, UniProt: Q9GZQ8 |
| Catalog # | MBS9205943 |
| Price | $165, $370 |
| Order / More Info | Cleaved LC3B, 89-122 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Baehrecke EH. Nat Rev Mol Cell Biol. 6(6):505-10. (2005) 2.Lum JJ, et al. Nat Rev Mol Cell Biol. 6(6):439-48. (2005) 3.Greenberg JT. Dev Cell. 8(6):799-801. (2005) 4. Levine B. Cell. 120(2):159-62. (2005) 5.Shintani T and Klionsky DJ. Science. 306(5698):990-5. (2004) 6.Tanida I., et al. Int. J. Biochem. Cell Biol. 36:2503-2518(2004) 7.He H., et al. J. Biol. Chem. 278:29278-29287(2003) 8.Tanida I., et al. J. Biol. Chem. 279:36268-36276(2004) References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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