Mucin-5AC Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Mucin-5AC |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human. Background: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a direct and critical mediator of resistance during intestinal nematode infection. |
| Immunogen | Immunogen: E Coli-derived human Mucin-5AC recombinant protein (Position: D4848-H5030). Ig Type: Rabbit IgG |
| Other Names | [Mucin-5AC; Apomucin; Gastric mucin; LeB; Lewis B blood group antigen; Major Airway Glycoprotein; MUC 5; MUC5; MUC5AC; Mucin 5 subtype AC tracheobronchial; Mucin 5 Subtypes A And C; Mucin 5 subtypes A and C tracheobronchial/gastric; Mucin 5AC; Mucin 5AC oligomeric mucus/gel forming; Mucin 5AC, oligomeric mucus/gel forming pseudogene; TBM; Tracheobronchial Mucin; mucin 5AC, oligomeric mucus/gel-forming], [MUC5AC; MUC5AC; TBM; leB; MUC5; mucin; TBM] |
| Gene, Accession # | Gene ID: 4586, NCBI: NP_001291288.1, UniProt: P98088 |
| Catalog # | MBS178193 |
| Price | $315 |
| Order / More Info | Mucin-5AC Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hasnain, S. Z., Evans, C. M., Roy, M., Gallagher, A. L., Kindrachuk, K. N., Barron, L., Dickey, B. F., Wilson, M. S., Wynn, T. A., Grencis, R. K., Thornton, D. J. Muc5ac: a critical component mediating the rejection of enteric nematodes. J. Exp. Med. 208: 893-900, 2011. 2. Moehle, C., Ackermann, N., Langmann, T., Aslanidis, C., Kel, A., Kel-Margoulis, O., Schmitz-Madry, A., Zahn, A., Stremmel, W., Schmitz, G. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease. J. Molec. Med. 84: 1055-1066, 2006. 3. Wang G, Xu Z, Wang R, Al-Hijji M, Salit J, Strulovici-Barel Y, Tilley A, Mezey J, Crystal R (June 2012). Genes associated with MUC5AC expression in small airway epithelium of human smokers and nonsmokers. BMC Med Genomics5 (1): 21. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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