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Antigenic Specificity | E2F1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed: 20176812). |
Immunogen | Immunogen: A synthesized peptide derived from human E2F1. Subcellular Localization: Nucleus. |
Other Names | [Transcription factor E2F1; E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1; E2F1; RBBP3], [E2F1; E2F1; RBP3; E2F-1; RBAP1; RBBP3; RBBP3; E2F-1; RBAP-1; RBBP-3] |
Gene, Accession # | [E2F1], Gene ID: 1869, NCBI: NP_005216.1, UniProt: Q01094 |
Catalog # | MBS179227 |
Price | $160, $340, $340 |
Order / More Info | E2F1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |