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Antigenic Specificity | ISGF3/IRF9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human ISGF3/IRF9. Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosinephosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3transcription factor, that enters the nucleus. |
Immunogen | Immunogen: Recombinant protein of human IRF9 encoding aa 113-255 Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human ISGF3/IRF9; IRF9; Interferon regulatory factor 9; ISGF3 p48 subunit; ISGF3G; p48; IRF-9; ISGF3; ISGF-3 gamma] |
Gene, Accession # | [ISGF3/IRF9], Gene ID: 10379, NCBI: NP_006075.3, UniProt: Q00978 |
Catalog # | MBS2401496 |
Price | $530 |
Order / More Info | ISGF3/IRF9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |