ACTR3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityACTR3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, monkey
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionActin nucleation, the formation of new actin filaments from existing filaments, affects actin filament structure during cell motility, division, and intracellular trafficking. An important actin nucleation protein complex is the highly conserved ARP2/3 complex, consisting of ARP2, ARP3, and ARPC1-5. The ARP2/3 complex promotes branching of an existing actin filament and formation of a daughter filament following activation by nucleation-promoting factors, such as WASP/WAVE or cortactin (1). The formation of podosomes, small cellular projections that degrade the extracellular matrix, is enhanced by ARP2/3 complex action. ARP2/3 competes with caldesmon, an actin binding protein shown to negatively affect podosome formation (2). Along with N-W
ImmunogenImmunogen: Recombinant Protein
Other Names[ACTR3; ARP3], [ACTR3; ACTR3; ARP3; ARP3]
Gene, Accession #[ACTR3], Gene ID: 10096, NCBI: P61158.3, UniProt: P61158
Catalog #MBS127721
Price$200, $275, $430
Order / More InfoACTR3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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