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Antigenic Specificity | BCMA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry-Paraffin (IHC-P), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BCMA Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-κB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. |
Immunogen | Immunogen: BCMA antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA. The immunogen is located within the last 50 amino acids of BCMA. |
Other Names | [BCMA; BCM; BCMA; CD269; TNFRSF13A; BCM; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; tumor necrosis factor receptor superfamily, member 17], [TNFRSF17; TNFRSF17; BCM; BCMA; CD269; TNFRSF13A; BCM; BCMA] |
Gene, Accession # | [TNFRSF17], Gene ID: 608, NCBI: NP_001183, UniProt: Q02223 |
Catalog # | MBS151091 |
Price | $375 |
Order / More Info | BCMA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |