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Antigenic Specificity | Human CD184 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises the human G-protein-coupled chemokine receptor CD184 (CXCR4), a 40kDa cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease, see Taniuchi, S. et al. for details. Rabbit anti Human CD184 antibody recognizes the human G-protein-coupled chemokine receptor CD184, also known as CXCR4. CD184 is a 352 amino acid ~40kDa cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells (Bleul et al. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease (Taniuchi et al.). |
Immunogen | Immunogen: Peptide sequence corresponding to amino acids 1-14 of human CD184. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human CD184 were raised by repeated immunisation of rabbits with highly purified antigen. Target Species: Human |
Other Names | [C-X-C chemokine receptor type 4 isoform a; C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; CD184 antigen; LPS-associated protein 3; SDF-1 receptor; fusin; leukocyte-derived seven transmembrane domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; chemokine (C-X-C motif) receptor 4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; Lipopolysaccharide-associated protein 3; LAP-3; LPS-associated protein 3; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD_antigen: CD184], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor] |
Gene, Accession # | [CD184], Gene ID: 7852, NCBI: NP_001008540.1, UniProt: P61073 |
Catalog # | MBS221580 |
Price | $375 |
Order / More Info | Human CD184 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |