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Antigenic Specificity | Mouse CD86/B7-2 |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD86, the B7-2 co-stimulatory molecule and a ligand for CD28 and CD152/CTLA-4. CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells. |
Immunogen | Immunogen: LPS-activated mouse B cells Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide. |
Other Names | [CD86-B7-2] |
Gene, Accession # | [CD86/B7-2] |
Catalog # | MBS4151785 |
Price | $445 |
Order / More Info | Mouse CD86/B7-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |