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Antigenic Specificity | PKN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PKN Polyclonal Antibody detects endogenous levels of PKN protein. The protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms h |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human PKN |
Other Names | [Rabbit PKN; PKN1; PAK1; PKN; PRK1; PRKCL1; Serine/threonine-protein kinase N1; Protease-activated kinase 1; PAK-1; Protein kinase C-like 1; Protein kinase C-like PKN; Protein kinase PKN-alpha; Protein-kinase C-related kinase 1; Serine-threonine protein] |
Gene, Accession # | [PKN], Gene ID: 5585, NCBI: NP_002732.3, UniProt: Q16512 |
Catalog # | MBS9706415 |
Price | $130, $220, $325 |
Order / More Info | PKN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |