Human CD152-Fab Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD152-Fab
Clone[ANC152.2/8H5]
Host SpeciesMouse
Reactive Specieshuman, porcine, cow, cat, dog
IsotypeIgG1k
Formatunconjugated
Size0.1 mg
Concentration1.0 mg/ml
ApplicationsFlow Cytometry (FC/FACS), ELISA (EIA), FX, Blocking
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DescriptionInformation: Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Antibody ANC152.2 reacts with CTLA-4 expressed on activated T cells. ANC152.2 binds to CD152 present on activated T cells, and blocks binding of recombinant CD152 (CTLA-4) fusion protein to CD80/CD86 receptors.
ImmunogenImmunogen: Stimulated human PBL's and human CD152 Ig fusion protein
Other Namesn/a
Gene, Accession #[CD152]
Catalog #MBS666017
Price$1020
Order / More InfoHuman CD152-Fab Antibody from MYBIOSOURCE INC.
Product Specific ReferencesT. Lindsten, et al, (1993) J Immunol 151: 3489-3499. T.L. Walunas, et al, (1994) Immunity 1:405-413. N.J. Karandikar, et al, (1996) J Exp Med 184: 783-788. A. Kitani, et al, (2000) J Immunol 165: 691-702.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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