F2RL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityF2RL1
Clonepolyclonal
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionReceptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation. Can signal synergistically with TLR4 and probably TLR2 in inflammatory responses and modulates TLR3 signaling. Has a protective role in establishing the endothelial barrier; the activity involves coagulation factor X
ImmunogenImmunogen: Recombinant Human Proteinase-activated receptor 2 protein (348-397AA) Raised In: Rabbit Species Reactivity: Human Conjugate: Non-conjugated Species: Human
Other Names[Proteinase-activated receptor 2,PAR-2,Coagulation factor II receptor-like 1,G-protein coupled receptor 11,Thrombin receptor-like 1,Proteinase-activated receptor 2,alternate cleaved 1,Proteinase-activated receptor 2,alternate cleaved 2,F2RL1,GPR11,PAR2]
Gene, Accession #[F2RL1], Gene ID: 2150, NCBI: NP_005233.3, UniProt: P55085
Catalog #MBS7051925
Price$160, $235
Order / More InfoF2RL1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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