Human CD193 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD193
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsImmunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB)
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DescriptionRabbit anti Human CD193 antibody recognizes human CD193, otherwise known as CC chemokine receptor 3 (CCR3), a seven-helix transmembrane G-protein coupled receptor which, along with CCR5 and CXCR4, acts as a principal receptor for the fusion and entry of HIV into target cells. CD193 is expressed by eosinophils, basophils, mast cells, microglia, Th2 helper cells and some epithelial cells. CD193 acts as a receptor for several CC chemokines including monocyte chemoattractant proteins (MCP) -1, -2, -3 and -4, MIP-1a, MIP-1beta, and RANTES. The eotaxin subgroup of CC chemokines act as specific agonists for CD193, and this interaction has become a focus area for studies into the infection of microglia by HIV (He, J. et al. 1997) and allergy resear
ImmunogenHistology Positive Control Tissue: Human spleen. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human CD193 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human
Other Names[C-C chemokine receptor type 3 isoform 1; C-C chemokine receptor type 3; C-C chemokine receptor type 3; C-C CKR-3; CC chemokine receptor 3; CCR-3; b-chemokine receptor; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; chemokine (C-C motif) receptor 3; Eosinophil eotaxin receptor; CD_antigen: CD193], [CCR3; CCR3; CKR3; CD193; CMKBR3; CC-CKR-3; CMKBR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3]
Gene, Accession #[CD193], Gene ID: 1232, NCBI: NP_001828.1, UniProt: P51677
Catalog #MBS221319
Price$375
Order / More InfoHuman CD193 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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