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Antigenic Specificity | Human CD193 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human CD193 antibody recognizes human CD193, otherwise known as CC chemokine receptor 3 (CCR3), a seven-helix transmembrane G-protein coupled receptor which, along with CCR5 and CXCR4, acts as a principal receptor for the fusion and entry of HIV into target cells. CD193 is expressed by eosinophils, basophils, mast cells, microglia, Th2 helper cells and some epithelial cells. CD193 acts as a receptor for several CC chemokines including monocyte chemoattractant proteins (MCP) -1, -2, -3 and -4, MIP-1a, MIP-1beta, and RANTES. The eotaxin subgroup of CC chemokines act as specific agonists for CD193, and this interaction has become a focus area for studies into the infection of microglia by HIV (He, J. et al. 1997) and allergy resear |
Immunogen | Histology Positive Control Tissue: Human spleen. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human CD193 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [C-C chemokine receptor type 3 isoform 1; C-C chemokine receptor type 3; C-C chemokine receptor type 3; C-C CKR-3; CC chemokine receptor 3; CCR-3; b-chemokine receptor; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; chemokine (C-C motif) receptor 3; Eosinophil eotaxin receptor; CD_antigen: CD193], [CCR3; CCR3; CKR3; CD193; CMKBR3; CC-CKR-3; CMKBR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3] |
Gene, Accession # | [CD193], Gene ID: 1232, NCBI: NP_001828.1, UniProt: P51677 |
Catalog # | MBS221319 |
Price | $375 |
Order / More Info | Human CD193 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |