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Antigenic Specificity | Phospho-MAPK8/9/10-T183/Y185 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 i |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T183/Y185 of human MAPK8/MAPK9/MAPK10 Calculated Molecular Weight: 46/54kDa |
Other Names | [Phospho-MAPK8/MAPK9/MAPK10-T183/Y185: JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c/JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA/JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK], [MAPK8; MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c] |
Gene, Accession # | [MAPK8/MAPK9/MAPK10], Gene ID: 5599, NCBI: P45983.2, UniProt: P45983 |
Catalog # | MBS128276 |
Price | $235, $350, $525 |
Order / More Info | Phospho-MAPK8/9/10-T183/Y185 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |