Phospho-MAPK8/9/10-T183/Y185 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAPK8/9/10-T183/Y185
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionResponds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 i
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding T183/Y185 of human MAPK8/MAPK9/MAPK10 Calculated Molecular Weight: 46/54kDa
Other Names[Phospho-MAPK8/MAPK9/MAPK10-T183/Y185: JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c/JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA/JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK], [MAPK8; MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c]
Gene, Accession #[MAPK8/MAPK9/MAPK10], Gene ID: 5599, NCBI: P45983.2, UniProt: P45983
Catalog #MBS128276
Price$235, $350, $525
Order / More InfoPhospho-MAPK8/9/10-T183/Y185 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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