Caspase-6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Caspase-6 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. Caspase-6 has known functions in apoptosis, early immune response and neurodegenration in Huntington's and Alzheimer's disease. Caspase-6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspase-6 plays a role in the early immune response via de-repression. It reduces the expression of the immunosuppressant cytokine interleukin-10 and cleaves the macrophage suppressing IRAK-M. With respect to neurodegeneration, caspase-6 cleaves HTT in Huntington's and APP in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode different isoforms. |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to Caspase-6 protein. |
| Other Names | [Apoptotic protease Mch-2; MCH2], [CASP6; CASP6; MCH2; MCH2; CASP-6] |
| Gene, Accession # | [CASP-6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
| Catalog # | MBS435299 |
| Price | $350, $565 |
| Order / More Info | Caspase-6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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