Human Interferon stimulated gene 15 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Interferon stimulated gene 15
Clone[P3E5AT]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1 k
FormatProtein G purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionIntroduction: ISG15 ubiquitin-like Modifier is conjugated to the intracellular target proteins after IFN-alpha or IFN-beta stimulation. ISG15 enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the ub conjugation pathway at the level of a specific E2 enzyme. ISG15 protein targets include STAT1, SERPINA 3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MXA, and RIG-1. Deconjugated by USP18/UBP43 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. ISG15 serves as a trans-acting binding factor directing
ImmunogenImmunogen: Anti-human ISG15 mAb is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ISG15 amino acids 1-157 purified from E Coli.
Other Namesn/a
Gene, Accession #[ISG15], NCBI: AGG15966.1
Catalog #MBS140275
Price$140, $205, $505
Order / More InfoHuman Interferon stimulated gene 15 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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