Edit |   |
---|---|
Antigenic Specificity | DAXX - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 through direct protein-protein interactions. Modulates PAX5 activity; the function seems to involve CREBBP. Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 li |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse DAXX |
Other Names | [death domain-associated protein 6; Death domain-associated protein 6; death domain-associated protein 6; Fas death domain-associated protein; Daxx] |
Gene, Accession # | [DAXX], Gene ID: 13163, NCBI: NP_001186662.1, UniProt: O35613 |
Catalog # | MBS3224190 |
Price | $335 |
Order / More Info | DAXX - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |