CD46, Mouse Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD46, Mouse
CloneMM10
Host SpeciesRat
Reactive Speciesreactivity: mouse. cross reactivity: rat
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsF, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunofluorescence (IF), Western Blot (WB)
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DescriptionProduct Description: The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic N
ImmunogenImmunogen: Mouse CD46-human Fc fusion protein
Other Names[MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10]
Gene, Accession #[CD46], Gene ID: 4179, NCBI: BAA12224.1
Catalog #MBS584300
Price$520
Order / More InfoCD46, Mouse Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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