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Antigenic Specificity | CD46, Mouse |
Clone | MM10 |
Host Species | Rat |
Reactive Species | reactivity: mouse. cross reactivity: rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | F, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic N |
Immunogen | Immunogen: Mouse CD46-human Fc fusion protein |
Other Names | [MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
Gene, Accession # | [CD46], Gene ID: 4179, NCBI: BAA12224.1 |
Catalog # | MBS584300 |
Price | $520 |
Order / More Info | CD46, Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |