Edit |   |
---|---|
Antigenic Specificity | ABIN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ABIN3 Antibody: The nuclear factor NF-κB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-κB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-κB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-κB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-κB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downre |
Immunogen | Immunogen: ABIN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ABIN3. Buffer: ABIN3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [LIND; ABIN-3; ABIN3; LIND; TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; TNFAIP3 interacting protein 3], [TNIP3; TNIP3; LIND; ABIN-3; ABIN-3] |
Gene, Accession # | [TNIP3], Gene ID: 79931, NCBI: NP_079149, UniProt: Q96KP6 |
Catalog # | MBS151164 |
Price | $375 |
Order / More Info | ABIN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |