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Antigenic Specificity | GOPC - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against GOPC. It was validated on Western Blot using a cell lysate as a positive control.Target Description: GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM] |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GOPC |
Other Names | [Golgi-associated PDZ and coiled-coil motif-containing protein isoform b; Golgi-associated PDZ and coiled-coil motif-containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; golgi associated PDZ and coiled-coil motif containing; CFTR-associated ligand; Fused in glioblastoma; PDZ protein interacting specifically with TC10; PIST] |
Gene, Accession # | [GOPC], Gene ID: 57120, NCBI: NP_001017408, UniProt: Q9HD26 |
Catalog # | MBS3212635 |
Price | $335 |
Order / More Info | GOPC - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |