PTP1B Picoband Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PTP1B Picoband |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Tyrosine-protein phosphatase non-receptor type 1, also known as protein-tyrosine phosphatase 1B (PTP1B), is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphor |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PTP1B (4-30aa EKEFEQIDKSGSWAAIYQDIRHEASDF), different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids. Subcellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Interacts with EPHA3 at the cell membrane. |
| Other Names | [Tyrosine-protein phosphatase non-receptor type 1; 3.1.3.48; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B] |
| Gene, Accession # | [PTP1B], Gene ID: 5770, NCBI: NP_001265547.1, UniProt: P18031 |
| Catalog # | MBS1750447 |
| Price | $315 |
| Order / More Info | PTP1B Picoband Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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