Human VEGFR-2/KDR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman VEGFR-2/KDR
Clone[IgG1; EWC]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionThe antibody will detect native human VEGFR-2/KDR in ELISA experiments and on the surface of different human cell types. VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D
ImmunogenImmunogen: recombinant human soluble KDR (D7) (RT# S01-002)recombinant human soluble KDR (D7) (RT# S01-002)
Other Names[human VEGFR-2/KDR (#EWC); Vascular endothelial growth factor receptor 2], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR]
Gene, Accession #[VEGFR-2/KDR], Gene ID: 3791, NCBI: NP_002241.1, UniProt: P22333
Catalog #MBS690191
Price$365
Order / More InfoHuman VEGFR-2/KDR Antibody from MYBIOSOURCE INC.
Product Specific References1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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