Edit |   |
---|---|
Antigenic Specificity | MYL2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MYL2 antibody detects endogenous levels of total MYL2. Description: MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle.Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.Subunit Structure: Myosin is a hexame |
Immunogen | Immunogen: Purified recombinant fragment of human MYL2 expressed in E. Coli Tissue Specificity: Smooth muscle tissues and in some, but not all, nonmuscle cells. |
Other Names | [Myosin light chain regulatory B; Myosin regulatory light chain 2 B, smooth muscle isoform; RLC B] |
Gene, Accession # | [MYL2], Gene ID: 10398, NCBI: NP_006088.2, UniProt: P24844 |
Catalog # | MBS9602378 |
Price | $235, $295, $370 |
Order / More Info | MYL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |