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Antigenic Specificity | COL18A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: COL18A1 Polyclonal Antibody detects endogenous levels of COL18A1 protein. COL18A1 (collagen type XVIII alpha 1 chain) encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in COL18A1 are associated with Knobloch syndrome. Th |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human COL18A1 at AA range: 1270-1350 |
Other Names | [Rabbit COL18A1; COL18A1; Collagen alpha-1(XVIII) chain] |
Gene, Accession # | [COL18A1], Gene ID: 80781, NCBI: NP_085059.2, UniProt: P39060 |
Catalog # | MBS9707246 |
Price | $130, $220, $325 |
Order / More Info | COL18A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |