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Antigenic Specificity | CSE1L - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CSE1L. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apop |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSE1L |
Other Names | [exportin-2 isoform 1; Exportin-2; exportin-2; chromosome segregation 1 like; Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter] |
Gene, Accession # | [CSE1L], Gene ID: 1434, NCBI: NP_001307, UniProt: P55060 |
Catalog # | MBS3224319 |
Price | $335 |
Order / More Info | CSE1L - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |