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Antigenic Specificity | SR-2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SR-2C Polyclonal Antibody detects endogenous levels of SR-2C protein. HTR2C encodes a seven-transmembrane G-protein-coupled receptor. The 5-hydroxytryptamine receptor 2C responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding a |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human SR-2C at AA rangle: 130-210 |
Other Names | [Rabbit SR-2C; HTR2C; HTR1C; 5-hydroxytryptamine receptor 2C; 5-HT-2C; 5-HT2C; 5-HTR2C; 5-hydroxytryptamine receptor 1C; 5-HT-1C; 5-HT1C; Serotonin receptor 2C] |
Gene, Accession # | [SR-2C], Gene ID: 3358, NCBI: NP_000859.1, UniProt: P28335 |
Catalog # | MBS9705441 |
Price | $130, $220, $325 |
Order / More Info | SR-2C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |