Mouse Dnmt3b (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Dnmt3b (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.08 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Dnmt3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the Central region of Mouse Dnmt3b. Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter h |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); DNA (cytosine-5)-methyltransferase 3B; Dnmt3b; DNA methyltransferase MmuIIIB; DNA MTase MmuIIIB; MMmuIIIB; Dnmt3b] |
| Gene, Accession # | [Dnmt3b], Gene ID: 13436, NCBI: NP_001003960.2, UniProt: O88509 |
| Catalog # | MBS9216213 |
| Price | $150 |
| Order / More Info | Mouse Dnmt3b (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Okano M.,et al.Nat. Genet. 19:219-220(1998).Yin B.,et al.Zhongguo Yi Xue Ke Xue Yuan Xue Bao 21:431-438(1999).Okano M.,et al.Cell 99:247-257(1999).Gowher H.,et al.J. Biol. Chem. 277:20409-20414(2002).Christophorou M.A.,et al.Nature 507:104-108(2014). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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