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Antigenic Specificity | TNF-R II, Human |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), FS, Immunoassay (IA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The polyclonal antibody recognizes the extracellular part of the human Tumor Necrosis Factor Receptor type 2 (TNF-RII) of the membrane-bound as well as the soluble receptor. TNF-RII (~75-80 kDa) is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-alpha activates inflammatory responses, induces apoptosis, regulates cellular proliferation, and may even promote cancer progression. The effects of TNF-alpha are mediated by TNF-RI and TNF-RII, which have both distinct and overlapping downstream signaling cascades. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membra |
Immunogen | n/a |
Other Names | [Tumor necrosis factor receptor superfamily member 1B, TNF-RII, p75/p80], [TNFRSF1B; TNF-RII/TNFRSF1B; TNF-RII/TNFRSF1B] |
Gene, Accession # | [TNF-R II], Gene ID: 338033, NCBI: ADU17359.1 |
Catalog # | MBS584499 |
Price | $610 |
Order / More Info | TNF-R II, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |