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Antigenic Specificity | Human p75NTR |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat, sheep |
Isotype | IgG |
Format | Protein G purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognises p75NTR (low affinity neurotrophin receptor). Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) due to its molecular mass and its ability to bind at low affinity not only NGF (see 162030), but also other neurotrophins, including brain-derived neurotrophic factor (BDNF; 113505), neurotrophin-3 (NTF3; 162660), and neurotrophin-4/5 (NTF5; 162662). At the time of its discovery, NGFR was considered a unique type of protein. Subsequently, however, a large superfamily of tumor necrosis factor receptors were found to share the overall structure of NGFR (4 extracellular ligand-binding, cysteine-rich repeats, or CRs, and signaling through association with, or disassociation from, cytoplasmic interactors). The |
Immunogen | Immunogen: The p75NTR antibody was derived from immunization of mice with human WM245 melanoma cells. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [p75 NTR] |
Gene, Accession # | [p75NTR] |
Catalog # | MBS4152678 |
Price | $515 |
Order / More Info | Human p75NTR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |