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Antigenic Specificity | DNMT3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using DNMT3A antibody. Immunofluorescence analysis of U2OS cell using DNMT3A antibody. Blue: DAPI for nuclear staining. Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development (1, 2). Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3 (1, 2). DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. DNMT3A and DNMT3B are strongly expressed in embryonic stem cel |
Immunogen | Immunogen: Recombinant protein of human DNMT3A |
Other Names | [DNA (cytosine-5)-methyltransferase 3A isoform d; DNA (cytosine-5)-methyltransferase 3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase 3 alpha; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIA], [DNMT3A; DNMT3A; TBRS; DNMT3A2; M.HsaIIIA; Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA] |
Gene, Accession # | [DNMT3A], Gene ID: 1788, NCBI: NP_001307822.1, UniProt: Q9Y6K1 |
Catalog # | MBS419964 |
Price | $385 |
Order / More Info | DNMT3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |