Human CD35 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD35
Clone[AR2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size100 tests
ConcentrationTitered for flow cytometry when used as indicated below. PBMc: Add 10 ul of MAB/10^6 PBMc in 100 ul PBS. Mix gently and incubate for 15 minutes at 2 degree to 8 degree c. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS a
ApplicationsFlow Cytometry (FC/FACS)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionComplement Receptor-1 (CR-1), CD35 complex is four different allotypes (C,A,B,D) C is 160 kDa; A is 190 kDa; B is 220 kDa and D is 250 kDa. It is involved in the processing of immune complexes, promoting of binding and phagocytosis of C3b complexes and inhibition of complement activation. CR-1 is on neutrophils, eosinophils, monocytes, B-cells, some NK-cells, erythrocytes, myeloid leukemias, follicular dendritic reticulum cells and is negative on basophils.
ImmunogenImmunogen: CD35=Derived from the hybridization od mouse SP2/0 cells with spleen cells of mice immunized with purified CR1
Other Names[CD35 FITC], [CR1; CR1; KN; C3BR; C4BR; CD35; C3BR]
Gene, Accession #[CD35], Gene ID: 1378, NCBI: NP_000642.3, UniProt: P17927
Catalog #MBS397657
Price$255
Order / More InfoHuman CD35 Antibody from MYBIOSOURCE INC.
Product Specific References1. Differential effects of the stimulation of complement receptors CR1 (CD35) and CR2 (CD21) on cell proliferation and intracellular Ca2 mobilization of chronic lymphocytic leukemia B cells. Hivroz C; Fischer E; Kazatchkine MD; Grillot-Courvalin C J Immunol 1991 Mar 1;146(6):1766-72 2. The C3b/C4b receptor is recognized by the Knops, McCoy, Swain-langley, and York blood group antisera. Moulds JM; Nickells MW; Moulds JJ; Brown MC; Atkinson JP J Exp Med 1991 May ;173(5):1159-63 3. Deduction from Wilms' tumour that glomerular podocytes produce the basement membrane material bearing Goodpasture determinants. Droz D; Diebold N; Jan D; Jaubert F J Pathol 1990 De;162(4):323-7 4. Purification and characterization of IgG immunoconglutinins from patients with systemic lupus erythematosus: implications for a regulatory function. Nilsson B; Ekdahl KN; Svarvare M; Bjel Clin Exp Immunol 1990 No;82(2):262-7 5. Granulocyte-macrophage colony-stimulating factor increases synthesis and expression of CR1 and CR3 by human peripheral blood neutrophils. Neuman E; Huleatt JW; Jack RM J Immunol 1990 Nov 1;145(10):3325-32 6. Expression of CR1 (CD35) mRNA in podocytes from adult and fetal human kidneys. Appay MD; Kazatchkine MD; Levi-Strauss M; Hinglais N; Bariety J Kidney Int 1990 Au;38(2):289-93 7. Complement receptor type 1 (C3b/C4b receptor; CD35) and complement receptor type 2 (C3d/Epstein-Barr virus receptor; CD21). Fearon DT; Ahearn JM Curr Top Microbiol Immunol 1990;153 p83-98
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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