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Antigenic Specificity | Human AICDA / AID |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to 14 amino acids near the carboxy-terminus of human AID. Activation-induced cytidine deaminase (AICDA) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. AICDA is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. |
Immunogen | Immunogen Description: Synthetic peptide from human AICDA. |
Other Names | [AICDA / AID (C-Terminus) IHC-plus; AICDA; AID; ARP2; CDA2; Cytidine aminohydrolase; HIGM2; Human AICDA; AID], [AID] |
Gene, Accession # | [AICDA], Gene ID: 57379, NCBI: NP_065712.1, UniProt: Q9GZX7 |
Catalog # | MBS240804 |
Price | $530 |
Order / More Info | Human AICDA / AID Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |