CCR3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCCR3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionCCR3 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results ind
ImmunogenImmunogen: CCR3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CCR3. Buffer: CCR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[CCR3; CKR3; CD193; CMKBR3; CC-CKR-3; C-C chemokine receptor type 3; Eosinophil eotaxin receptor; C-C CKR-3; chemokine (C-C motif) receptor 3], [CCR3; CCR3; CKR3; CD193; CMKBR3; CC-CKR-3; CMKBR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3]
Gene, Accession #[CCR3], Gene ID: 1232, NCBI: NP_847899, UniProt: P51677
Catalog #MBS150409
Price$375
Order / More InfoCCR3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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