Caspase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-3
Clone[1H11-G3-F8]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the sa
ImmunogenImmunogen: Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.
Other Names[caspase-3 isoform a preproprotein; Caspase-3; caspase-3; caspase 3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1]
Gene, Accession #[CASP3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574
Catalog #MBS8539453
Price$280
Order / More InfoCaspase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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