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Antigenic Specificity | PPL (C-term), 1301-1330 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.45 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1301-1330 amino acids from the C-terminal region of human PPL. The protein encoded by this gene is a component ofdesmosomes and of the epidermal cornified envelope inkeratinocytes. The N-terminal domain of this protein interacts withthe plasma membrane and its C-terminus interacts with intermediatefilaments. Through its rod domain, this protein forms complexeswith envoplakin. This protein may serve as a link between thecornified envelope and desmosomes as well as intermediatefilaments. AKT1/PKB, a protein kinase mediating a variety of cellgrowth and survival signaling processes, is reported to interactwit |
Immunogen | n/a |
Other Names | [Periplakin; 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; PPL; KIAA0568] |
Gene, Accession # | [PPL], Gene ID: 5493, NCBI: NP_002696.3, UniProt: O60437 |
Catalog # | MBS9211788 |
Price | $165, $370 |
Order / More Info | PPL (C-term), 1301-1330 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010) : Huang, Y., et al. Arch. Dermatol. Res. 301(10):703-709(2009) Boczonadi, V., et al. Exp. Cell Res. 313(16):3579-3591(2007) |