PPL (C-term), 1301-1330 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPPL (C-term), 1301-1330
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.45
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1301-1330 amino acids from the C-terminal region of human PPL. The protein encoded by this gene is a component ofdesmosomes and of the epidermal cornified envelope inkeratinocytes. The N-terminal domain of this protein interacts withthe plasma membrane and its C-terminus interacts with intermediatefilaments. Through its rod domain, this protein forms complexeswith envoplakin. This protein may serve as a link between thecornified envelope and desmosomes as well as intermediatefilaments. AKT1/PKB, a protein kinase mediating a variety of cellgrowth and survival signaling processes, is reported to interactwit
Immunogenn/a
Other Names[Periplakin; 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; PPL; KIAA0568]
Gene, Accession #[PPL], Gene ID: 5493, NCBI: NP_002696.3, UniProt: O60437
Catalog #MBS9211788
Price$165, $370
Order / More InfoPPL (C-term), 1301-1330 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010) : Huang, Y., et al. Arch. Dermatol. Res. 301(10):703-709(2009) Boczonadi, V., et al. Exp. Cell Res. 313(16):3579-3591(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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