Phospho-PZR (Tyr263) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-PZR (Tyr263) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-PZR (Tyr263) Antibody detects endogenous levels of PZR only when phosphorylated at Tyr263. Description: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.Post Translational Modifications: Phosphorylated on tyrosine residues up |
| Immunogen | Immunogen: A synthesized peptide derived from human PZR around the phosphorylation site of Tyr263. Tissue Specificity: Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expr |
| Other Names | [immunoglobulin family transmembrane protein; MPZL1; MPZL1b; myelin protein zero like 1; Myelin protein zero like protein 1; myelin protein zero like protein 1 precursor; myelin protein zero like protein MPZL1b; OTTHUMP00000032519; protein zero related; PZR; PZR1b; PZRa; PZRb] |
| Gene, Accession # | [PZR], Gene ID: 9019, NCBI: NP_001139663.1, UniProt: O95297 |
| Catalog # | MBS9610528 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-PZR (Tyr263) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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