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Antigenic Specificity | WTAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed: 24316715, PubMed: 24407421, PubMed: 24981863). Acts as a mRNA splicing regulator (PubMed: 12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed: 17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed: 17095724). |
Immunogen | Immunogen: Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA) |
Other Names | [Pre-mRNA-splicing regulator WTAP; Female-lethal(2)D homolog; hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein; WTAP; KIAA0105] |
Gene, Accession # | [WTAP], Gene ID: 9589, NCBI: NP_001257460.1, UniProt: Q15007 |
Catalog # | MBS7050205 |
Price | $160, $235 |
Order / More Info | WTAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |