PUF60 (N-term), 15-43 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PUF60 (N-term), 15-43 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.35 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PUF60 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human PUF60. The protein encoded by this gene is a Ro RNP-bindingprotein. It interacts with Ro RNPs and their interaction is thoughtto represent a gain of function for Ro RNPs. This protein alsoforms a ternary complex with far upstream element (FUSE) andFUSE-binding protein. It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibitactivated transcription. This gene is implicated in the xerodermapigmentosum disorder. There are two alternatively splicedtranscript variants of this gene encoding different isoforms |
| Immunogen | n/a |
| Other Names | [Poly(U)-binding-splicing factor PUF60; 60 kDa poly(U)-binding-splicing factor; FUSE-binding protein-interacting repressor; FBP-interacting repressor; Ro-binding protein 1; RoBP1; Siah-binding protein 1; Siah-BP1; PUF60; FIR; ROBPI; SIAHBP1] |
| Gene, Accession # | [PUF60], Gene ID: 22827, NCBI: NP_001129505.1, UniProt: Q9UHX1 |
| Catalog # | MBS9208219 |
| Price | $165, $370 |
| Order / More Info | PUF60 (N-term), 15-43 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hsiao, H.H., et al. Biochemistry 49(22):4620-4634(2010) Corsini, L., et al. J. Biol. Chem. 284(1):630-639(2009) Gao, J., et al. Genomics 91(4):347-355(2008) Hastings, M.L., et al. PLoS ONE 2 (6), E538 (2007) : Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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