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Antigenic Specificity | MARCH8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 232-291 of human MARCH8 (NP 659458.2). |
Other Names | [MIR; CMIR; c-MIR; RNF178; MARCH-VIII] |
Gene, Accession # | [MARCH8], NCBI: NP_659458, UniProt: Q5T0T0 |
Catalog # | MBS8548492 |
Price | $280 |
Order / More Info | MARCH8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |