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Antigenic Specificity | CADM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CADM3 antibody detects endogenous levels of total CADM3. Function: Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).Subunit Structure: Homodimer. Can form trans-heterodimers with NECTIN3. Interacts with EPB41L1, DLG3, MPP6 and CASK (By similarity).Similarity: The cytoplasmic region mediates interaction with EPB41L1, DLG3, MPP6 and CASK. Belongs to the nectin family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Junction. Cell Membrane. Localized at the cell-cell attached sites of the plasma membrane. Tissue Specificity: Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbi |
Other Names | [BIgR; Brain immunoglobulin receptor; CADM 3; cadm3; CADM3_HUMAN; Cell adhesion molecule 3; Dendritic cell nectin like protein 1 short isoform; FLJ10698; IgSF4B; Immunoglobulin superfamily member 4B; Necl 1; Necl-1; NECL1; Nectin like 1; Nectin like protein 1; Nectin-like protein 1; Synaptic cell adhesion molecule 3; synCAM3; TSLC1 like 1; TSLC1 like protein 1; TSLC1-like protein 1; TSLL1] |
Gene, Accession # | [CADM3], Gene ID: 57863, NCBI: NP_001120645.1, UniProt: Q8N126 |
Catalog # | MBS9604994 |
Price | $240, $280 |
Order / More Info | CADM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |