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Antigenic Specificity | Human Interleukin-32 |
Clone | [PAT2F9AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: IL-32 is part of the cytokine family and contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. IL-32 expression is elevated after the activation of T-cells by mitogens or the activation of NK cells by IL-2. IL-32 induces the production of TNF-a from macrophage cells. IL-32 pro-inflammatory pathway is activated in response to influenza A virus infection. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Induction of TNF, IL-1beta, and IL-6 by IL-32 is intervened by p38-MAPK. IL-32 induced monocyte-to-macrophage differentiation is mediated through nonapo |
Immunogen | Immunogen: Anti-human IL32 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human IL32 amino acids 1-331 purified from E Coli. |
Other Names | [IL32; Interleukin-32, Mouse Human; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; Interleukin-32; IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor; IL-32a; IL32a; IL32; Interleukin-32 alpha], [IL32; IL32; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; NK4; TAIF; IL-32] |
Gene, Accession # | [IL32], Gene ID: 9235, NCBI: NP_001012649.1 |
Catalog # | MBS140348 |
Price | $140, $205, $505 |
Order / More Info | Human Interleukin-32 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |