Phospho-TIF-IA (Ser649) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-TIF-IA (Ser649) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-TIF-IA (Ser649) antibody detects endogenous levels of TIF-IA only when phosphorylated at Ser649. Function: Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).Subunit Structure: Interacts with TWISTNB, EIF3L, TAF1B and TAF1C.Post-translational Modifications: Phosphorylation is required for participation in rDNA transcription (By similarity). Phosphorylated at Thr-200 by MAPK9/JNK2, which abrogates initiation complex formation.Similarity: Belongs to the RRN3 family. |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-TIF-IA (Ser649) Subcellular Location: Nucleus > Nucleolus. |
| Other Names | [AL023001; DKFZp566E104; E130302O19Rik; MGC104238; R75565; RGD1305001; RNA polymerase I-specific transcription initiation factor RRN3; Rrn3; RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae); RRN3_HUMAN; TIF-IA; TIF1A; TIFIA; Transcription Initiation Factor 1A; Transcription initiation factor IA; Transcription initiation factor TIF IA] |
| Gene, Accession # | [TIF-IA], Gene ID: 54700, NCBI: NP_060897.3, UniProt: Q9NYV6 |
| Catalog # | MBS9609061 |
| Price | $240, $280 |
| Order / More Info | Phospho-TIF-IA (Ser649) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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