Human Bid Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Bid
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formataffinity purified
Size0.1 mg
Concentration100ug/200ul
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Human Bid. Members of the Bcl-2 family are pro-or antiapoptotic proteins that process one or several of the Bcl-2 homology (BH) domains. Bid is a proapoptotic, BH3-domain-only member or BH3-only protein (BOP) of the Bcl-2 family. Bid is localized in the cytosolic fraction of living cells as an inactive precursor. Activation of Bid occurs upon its cleavage by caspase-8 in the Fas and TNF-beta apoptotic signaling pathways. Recent studies have suggested that Bid is also cleaved and activated by granzyme B, calpain and lysosomal extracts. Cleaved Bid translocates to mitochondria where it induces the release of cytochrome c from the intermembrane space of the mitochondria. The release of cytochrome c initiates apoptosis by activatin
Immunogenn/a
Other Names[BID; BH3-interacting domain death agonist; BH3-interacting domain death agonist; BH3 interacting domain death agonist; p22 BID; BID]
Gene, Accession #[Bid], Gene ID: 637, NCBI: CAG30275.1, UniProt: P55957
Catalog #MBS4152612
Price$445
Order / More InfoHuman Bid Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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