p130 Cas (Phospho-Tyr410) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp130 Cas (Phospho-Tyr410)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of p130 Cas only when phosphorylated at tyrosine 410. Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535.Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863.Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189.Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas.
Other Names[BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE]
Gene, Accession #[p130 Cas], Gene ID: 9564, NCBI: NP_001164185.1, UniProt: P56945
Catalog #MBS9403264
Price$200, $255
Order / More Infop130 Cas (Phospho-Tyr410) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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