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Antigenic Specificity | p130 Cas (Phospho-Tyr410) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of p130 Cas only when phosphorylated at tyrosine 410. Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535.Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863.Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189.Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas. |
Other Names | [BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE] |
Gene, Accession # | [p130 Cas], Gene ID: 9564, NCBI: NP_001164185.1, UniProt: P56945 |
Catalog # | MBS9403264 |
Price | $200, $255 |
Order / More Info | p130 Cas (Phospho-Tyr410) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |