RhoB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRhoB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionRho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecu
ImmunogenImmunogen: Recombinant protein of humanRHOB Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[ARH6; ARHB; MST081; MSTP081; RHOH6]
Gene, Accession #[RhoB], Gene ID: 388, NCBI: NP_004031.1, UniProt: P62745
Catalog #MBS8500002
Price$310
Order / More InfoRhoB Antibody from MYBIOSOURCE INC.
Product Specific References1. DerMardirossian, C. and Bokoch, G.M. (2005) Trends Cell Biol 15, 356-63. 2. Wennerberg, K. and Der, C.J. (2004) J Cell Sci 117, 1301-12. 3. Wheeler, A.P. and Ridley, A.J. (2004) Exp Cell Res 301, 43-9. 4. Wheeler, A.P. and Ridley, A.J. (2007) Exp Cell Res 313, 3505-16. 5. Sandilands, E. et al. (2007) J Cell Sci 120, 2555-64. 6. Neel, N.F. et al. (2007) J Cell Sci 120, 1559-71. 7. Baldwin, R.M. et al. (2008) Oncogene 27, 3587-95. 8. Couderc, B. et al. (2008) Cancer Gene Ther 15, 456-64.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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