FEN-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FEN-1 |
| Clone | [1E7-A6-H6] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 1.25mg/ml |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another.The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication.DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded |
| Immunogen | Immunogen: Purified recombinant human FEN-1 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of FEN-1 and does not cross-react with related proteins. Sequence Similarities: Belongs to the XPG/RAD2 endonuclease family.FEN1 subfamily. |
| Other Names | [DNase IV; FEN-1; FEN1; FEN1_HUMAN; Flap endonuclease 1; Flap structure specific endonuclease 1; Flap structure-specific endonuclease 1; hFEN-1; hFEN1; Maturation factor 1; MF1; Rad2], [MF1; RAD2; FEN-1.] |
| Gene, Accession # | [FEN-1], Gene ID: 2237, NCBI: NP_004102.1, UniProt: P39748 |
| Catalog # | MBS475208 |
| Price | $335 |
| Order / More Info | FEN-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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