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Antigenic Specificity | DDX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 expression. Binds to the cyclin CCND2 promoter region. Associates with chromatin at the NF-kappa-B promoter region via association with RELA. Binds to poly(A) RNA. May be involved in 3'-end cleavage |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 441-740 of human DDX1 (NP 004930.1). |
Other Names | [DBP-RB; UKVH5d] |
Gene, Accession # | [DDX1], Gene ID: 1653, NCBI: NP_004930, UniProt: Q92499 |
Catalog # | MBS8546205 |
Price | $280 |
Order / More Info | DDX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |