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Antigenic Specificity | IRF2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. |
Immunogen | Immunogen: A synthesized peptide derived from human IRF2. Subcellular Localization: Nucleus. Tissue Specificity: Expressed throughout the epithelium of the colon. Also expressed in lamina propria. |
Other Names | [Interferon regulatory factor 2; IRF-2; IRF2], [IRF2; IRF2; IRF-2; IRF-2] |
Gene, Accession # | [IRF2], Gene ID: 3660, NCBI: NP_002190.2, UniProt: P14316 |
Catalog # | MBS179916 |
Price | $160, $340, $340 |
Order / More Info | IRF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |